Combining large-scale analyses of immune variability with accompanying functional information can advance future research into immune-mediated diseases and understand how variation among individuals underlies disease mechanisms. CD Genomics provides specialized functional genome sequencing and analysis services to advance basic immunology research and potential applications.
Functional genomics deals with genes, functions, and their interactions. High-throughput technologies are often used to conduct research in this area, generating a wealth of data. Disease susceptibility variants revealed through genome-wide association studies (GWAS) are quantitative trait loci (QTL), which provide causal information on intermediate traits between the genome and disease. A comprehensive understanding of these traits will facilitate the development of genomic function studies.
The Human Functional Genomics Project (HFGP) aims to identify genetic and non-genetic host factors that determine inter-individual variability in immune responses. Many studies based on immune functional genomics have been carried out to unravel the molecular basis of immune diversity.
Fig.1 Schematic study design of genome-wide functional genomics approach. (Chu, X., et al., 2022).
Functional genomics is the study of how genes and intergenomic regions contribute to different biological processes. Functional genomics for immune system is useful for identifying the mechanisms of action of disease-associated variants and the underlying mechanisms of complex diseases, leading to advances in translating genetic discoveries into the clinic.
CD Genomics has been engaged in immunomics research for many years and has a professional sequencing and related genotyping platform to provide professional, efficient, and large-scale functional genomics services and GWAS services to analyze the pathogenesis of a variety of diseases and develop potential therapies, including but not limited to the following fields.
In addition, CD Genomics has a professional data analysis team that can help clients analyze genomic data to process large-scale data and to identify potential disease-causing variants and disease-causing genes in autoimmunity.
Based on years of experience in immunomics research, CD Genomics offers reliable immune functional genomics studies to find loci associated with disease susceptibility, immunomodulatory diseases, and immune system function. Please contact us for more information.
